I have a picture of Jackie Robinson on my wall. It's there to remind me that when there's prejudice or hostility, the best way to address it is to do your job well.
I love that.
Although the concept of a "Last Lecture" is a longstanding tradition in American universities, I think it's fair to say that it will continue to be associated primarily with Randy Pausch for some time to come.
The title of Randy's lecture was Really Achieving Your Childhood Dreams.
I love that too.
The pdf transcript is here (248 KB).
The video is on Youtube: